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When diabetes is undetected or inadequately treated, people with diabetes are at risk of serious and life-threatening complications, such as heart attack, stroke, kidney failure, blindness, and lower-limb amputation

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Injection of a GLP1 bolus into the third ventricle increases glucose stimulated insulin secretion, whereas inhibition of central GLP1 receptors impairs glucose exchanges in response to an intraperitoneal glucose tolerance test (Table 3) (Sandoval et al., 2008)

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10.1016/j.ccl.2021.04.009 [DOI] [PubMed] [Google Scholar] 75.Papekov, I