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The insight most users miss: IGF-1 LR3's extended half-life (2030 hours vs 10 minutes for endogenous IGF-1) means systemic circulation, not localized muscle activation

In the OASIS 4 trial, oral Wegovy (25mg) produced 16.6% weight loss, which is comparable to injectable Wegovy (14.9% in STEP 1)

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Kosmaczewska A, Swierkot J, Ciszak L, Wiland P

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Step 2: Follow Dosage Guidelines Most sprays recommend 12 daily doses (2040 mg per spray)