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Emerging evidence further indicates that MTs particularly MT1 and MT2A constitute a critical cytoplasmic defense layer against cuproptosis by acting as effective copper sponges that sequester excess Cu + and restrict its aberrant interaction with mitochondrial targets 170,173,174

Even "gentle" concentrations (10-20%) that would be well-tolerated on healthy skin pose significant risk

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Shellfish also have B12, including clams, shrimp, and raw oysters

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Oncogene 18 , 35933607 (1999)