#Pharma has been aiming for years to achieve magnitude of #weightloss similar to #bariatricsurgery, and now multiagonists prove that can be achieved. * HOWEVER, not everyone needs bariatric surgical magnitude of wt loss (and the discontinuations due to perceived excessive wt loss in this reta trial prove this point)
Medical Impact In 2024, the NCD Risk Factor Collaboration (NCD-RisC) released data estimating that over one billion people worldwide are now living with obesity, including nearly 880 million adults and 159 million children and adolescents aged 519
10.1002/14651858.CD009825.pub2 67
Vitamin B12 is a water-soluble vitamin that occurs naturally in some foods, is added to others, and is accessible as both a dietary supplement and a prescription drug
Cardiologists, endocrinologists, and primary care providers should consider advocating for the use of semaglutide in high-risk CKM patients, given its potential to address interconnected metabolic, CV, and kidney disorders
(2020) found that Ruminococcus_bromii, Clostridium_methylpentosum, Roseburia_intestinalis, Clostridium_asparagiforme and Oscillibacter_valericigenes increased after Cyclocarya paliurus polysaccharide (CCPP) treatment
