Occasional mild injection-site reactions (redness, swelling) may occur
Travel friendly Great option for people facing a needle phobia But nothing matters more than the numbers
[PMC free article: PMC2276968] [PubMed: 18190611] 179
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The non-metabolizable glucose analog and SGLT-1 agonist, -methylglucopyranoside, is also a potent stimulator of GLP-1 release from primary intestinal L-cell cultures, highlighting this transporter as a major stimulator of hormone release from EECs ( ATP-sensitive potassium The ATP-sensitive potassium (K ATP ) channel subunits, Kir6.2 and Sur1, have been identified in primary L-cells expressed at levels similar to those seen in pancreatic cells, where they are known to be involved in insulin release (182)
Het systemische gevolg hiervan is een positieve feedback van hyperinsulinemie en een afname van de gevoeligheid van cellen voor glucose