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Patients should follow the guidance of their healthcare provider and refer to the instructions provided with their medication pen

The STEP-4 trial found that patients who switched from semaglutide 2.4 mg to placebo after 20 weeks regained approximately two-thirds of their prior weight loss over the next year, while those who stayed on 2.4 mg continued to lose (Rubino et al., JAMA 2021)

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