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The weight-loss drugs, which include Wegovy (semaglutide) and Zepbound (tirzepatide), have become more accessible than ever thanks to recent price cuts, expanding Medicare and Medicaid access, and (more controversially) compounded options from online pharmacies and health startups

Svegliati-BaroniGSaccomannoSRychlickiCAgostinelliLDe MinicisSCandelaresiCet al

Pricing is lower for longer plans

A simple way to monitor hydration is the color of your urine after you wake up: straw- or lemonade-colored urine is a sign of appropriate hydration, while dark-colored urine, about the color of apple juice, indicates dehydration

But getting enough nutrients is essential for weight loss, muscle maintenance, gut health and energy

The FLOW trial also highlights the renal protective effects of GLP-1RAs, suggesting a close link between renal and cardiovascular benefits, which warrants further mechanistic studies (256)