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A resazurin-based cell death assay also found no significant increase in cell death upon BSO treatment (Fig

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10.1186/s10194-021-01369-6 J

doi: 10.1186/s12916-023-02967-8 34

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While such models provide significant mechanistic insights into APAP-induced hepatotoxicity, including pathways related to oxidative stress, mitochondrial dysfunction, and inflammasome activation, they may not fully recapitulate the complexity of human physiology

References National Centre for Biotechnology Information: Harvard Health Publishing: American Academy of Dermatology: Indian Journal of Dermatology, Venereology, and Leprology: