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There have been postmarketing reports of acute renal failure, sometimes requiring dialysis
The synovium primarily consists of FLSs and immune cells
Some of the preclinical research has included preliminary results for: Inflammatory bowel disease: In mouse studies, KPV reduced inflammation and protected the gut barrier
10.1038/s41598-018-33385-z Summary Keywords nitazoxanide, methotrexate, hepatotoxicity, endoplasmic reticulum stress, rat Citation Mahmoud NM, Elshazly SM, El-shaarawy F, Zaitone SA, Aldahish AA, Ahmed GA, Fawzy MS, Aloyouni SY, Abed SY, Saeedi T and El-Sayed SS (2024) Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress
To address this, in 2022, Jia-Ying Zhou et al
Thomas JD, Dattani A, Zemrak F, Burchell T, Akker SA, Gurnell M, et al
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