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About this article Cite this article Dajti, E., Tripodi, V., Hu, Y
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2.3.1 Multiple sclerosis pathogenesis and BBB disruption The initiating events in MS involve aberrant activation of autoreactive lymphocytes in the periphery
Therapeutically, p53 activation dualistically regulates apoptosis and ferroptosis to suppress PCa growth, but ferroptosis-driven macrophage polarization in the TME may inadvertently promote tumor metastasis [Figure 2A], emphasizing the need for context-specific modulation to balance efficacy and paradoxical outcomes
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