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8 Blood glucose monitoring is required in these patients and reductions in sulfonylurea or insulin dosing may be necessary (see: Prescribing empagliflozin for guidance on dose adjustments)

This dose is the highest dose meeting tolerability and safety criteria in the phase I study of (in)GSH in PD

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33 MuraoK.LiJ.ImachiH.MuraokaT.MasugataH.ZhangG.et al (2009)

The subjects response time or motor function may become slightly impaired or decreased after administration of higher doses