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PMID 25485164

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GHK-Cu independently upregulates collagen I and collagen III gene expression while also keeping MMP activity in check, preventing premature matrix degradation [5]

Instead, the spectrum of most prevalent pulmonary diseases had shifted from opportunistic infections to chronic illnesses, such as emphysema, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and lung cancer which are discussed in more detail in a later section

Senescent immune cells under excessive loading contribute to age-related pathological changes, which can progress to age-related diseases