Some individuals may attempt to use doses lower than the licensed starting doses or remain at the initial dose indefinitely, rather than following the licensed escalation protocol
Individuals on Tirzepatide (n = 50) reported a median dose of 7.5 mg [range 0.515 mg], and on Semaglutide variants: Ozempic or Wegovy (n = 54) reported a median dose of 1 [range 0.252.4] and Rybelsus (n = 2) reported doses of 7 mg and 14 mg
Insurance companies may set higher thresholds
Singh SR, Ahmad F, Lal A, Yu C, Bai Z, Bennett H
doi: 10.1074/jbc.M307612200 116 BatistaAFBodart-SantosVDe FeliceFGFerreiraST
Noom Liraglutide uses the same active ingredient (liraglutide) as Saxenda, but Noom packages it with behavioral coaching, meal planning, and a digital app