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Cognitive improvement was observed after 8 weeks of treatment in both females and males, sustained through a 12-week study period, and accompanied by a concurrent reduction in amyloid plaques and neuroinflammation compared to intranasal saline-treated transgenic mice

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PARG inhibitor (PARGi) treatment was used as a positive control

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[4] Oncostatic Properties and Safety Considerations in Research Telomerase reactivation raises an immediate and legitimate concern: cancer cells universally upregulate telomerase to achieve replicative immortality, and any agent that activates hTERT theoretically risks contributing to oncogenesis

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70,71 In situations when the diagnosis is not certain, a doctor may collect material from the blisters to look for varicella-zoster virus DNA, which can confirm the diagnosis

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