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Warning signs include: Sudden rash or hives spreading across the body Generalized itching that is not isolated to the application site Swelling of the face, lips, tongue, or throat Difficulty breathing or shortness of breath Symptoms suggestive of a severe allergic reaction (anaphylaxis) require prompt medical attention

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease

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This effect was also seen in the striatum of HIV-infected, encephalitic brains (Meulendyke et al., 2014) and suggests that accelerated dopamine breakdown could produce ROS to increase myeloid cell activation and drive neuroinflammation