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The impact of Zn on adipocyte differentiation may be related to the functioning of various Zn-containing proteins that have been recognized as early regulators of adipogenesis [109]

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For instance, enhanced reduction of selenite and accelerated trans-selenation pathway for SeMet [analog of trans-sulfuration mechanism, transferring sulfur from methionine to serine to yield cysteine (Jackson et al., 2013)] may be additional sources of Se for selenophospate synthesis and consequently selenoprotein production (Seale, 2019)