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Roche experienced several setbacks in 2022, in their pipeline, against emerging biosimilars and a decline in their COVID-19 sales that resulted in just a 0.8 percent revenue increase over the past year

Liraglutide (a daily injection) resulted in an average 4-5% weight loss in 24 trials (9 937 participants), still outperforming placebo

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Researchers reviewing the topical glutathione literature have consistently called for larger trials with longer follow-up before it can be considered as well-established as those alternatives not because early results are bad, but because there simply isn't as much data yet