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Decisions about continuing or discontinuing Wegovy (semaglutide) should always be made in consultation with a healthcare provider

However, many people find that their body adapts more quickly to each subsequent dose increase because the underlying mechanisms (caloric deficit, metabolic adaptation) are already partially adjusted

Individual genetic variation in GLP-1 receptor sensitivity also influences how your body responds

While your liver naturally produces this compound, several factors can influence your internal levels

What does the article's table say a consistent caloric deficit does to the timeline

This timing also aligns with natural circadian hunger patterns, allowing the appetite-suppressing effects to support your most challenging eating periodsbreakfast through lunch