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Nonetheless, the exact mechanisms and implications of this regulation remain elusive and warrant further investigation

Chatelain PG, Sanchez P, Saez JM

That inversion is the central honest finding of this article

Chronic pain to me is you have one incident of back pain and you become centrally sensitized because of fear avoidance and true central nervous system changes

The breathing discomfort has been attributed to chronic changes in breathing pattern and persisting inflammation in lungs or mediastinal lymph nodes, as well as association of metabolic abnormalities with lung sequelae