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This biogenic program upregulates mitochondrial transcription factor A (TFAM) and electron transport chain (ETC) proteins, thereby increasing oxygen consumption and ATP/ADP ratios (Hodson et al., 2014

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In addition, ALCAR had no effect on the expression of the nerve growth factor receptors on SKOV-3 or OVCAR-3 ovarian cancer cells [1]

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PLoS ONE 10:e0134303 Mizunoya W, Okamoto S, Miyahara H et al (2017) Fast-to-slow shift of muscle fiber-type composition by dietary apple polyphenols in rats: impact of the low-dose supplementation