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Blog Causes of night sweatsand what you can do to address them Medically reviewed by William Ross Perlman, PhD, CMPP on January 10, 2020

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The potential limitations of certain studies may include the period of the research, as it may not adequately capture the long-term effects and potential negative effects of GLP-1 agonists

GLP-1 receptor agonists slow gastric emptying, which has been hypothesized to affect pancreatic function, though this connection remains speculative and lacks supporting clinical evidence

The side effect profile is well-documented, serious adverse events are rare, and long-term data is accumulating

Those findings suggest that the first histidine residue of GLP-1 and EX4 only plays a marginal role in activation of the GLP-1R when the peptide is fused to the receptor