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Key Findings The review synthesized data from 39 studies, including in vitro research, metabolite and co-factor studies, intervention trials, and genetic analyses

A common feature is immune dysregulation, where, in Graves disease, autoantibodies stimulating the thyroid to produce an excessive amount of hormone and, in Hashimotos thyroiditis, the thyroid gland suffers autoimmune destruction (Bari et al

Available from: Simon L et al (2014) Paternal influence of sperm DNA integrity on early embryonic development

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Again, the antioxidant action of DFO in vivo may be of little importance because the blood levels reached during therapy (20 M) are too low to achieve the desired effect (Halliwell and Gutteridge, 2015)

*Correspondence: Agnieszka Dylg, [email protected]