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This careful titration minimizes potential side effects, such as gastrointestinal discomfort, and allows your body to adapt to the medication

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Glucagon-like peptide-1 (GLP-1) action in the mouse area postrema neurons

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Endogenous GLP-1 acts in GLP-1Rs located in this region and reduces the intake of highly palatable foods by suppressing mesolimbic dopamine signaling, which controls the pleasure-directed acquisition of food [24]