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Thus, according to patent literature the drug-like 8 and 9 exhibit a very high affinity to the Ang IV binding site named the AT4 receptor

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Folate is a co-factor for enzymes that regulate DNA synthesis and methylation, and is more directly involved in these processes than B12---making it vital for proper gene expression as well as cell growth, repair, and division, especially during periods of rapid growth like pregnancy

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Vitamin B12 is essential for red blood cell production, nerve function, energy metabolism and the synthesis of DNA