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Genetic factors in glutathione metabolism pathways (e.g., GSTM1, GSTP1 variants) and peptide receptor sensitivity may influence how each agent works

KEY POINTS GPx-1 (glutathione peroxidase 1) is an enzyme that protects cells against damage from harmful substances called Reactive Oxygen Species (ROS)

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For this, 10 M wild type SnCE1 and inactive mutant C256A were incubated with 0.05 mM and 1 mM of acetyl group donor acetyl-CoA (Cayman Chemicals, cat no