Less frequent AEs like hypoglycemia, is mostly seen in combination with insulin or sulfonylureas (157) and some reports of pancreatobiliary complications are partially explained by direct altered absorption of bile acids, rapid weight loss or changes in the gallbladder motility with increased risk of pancreatitis, even though it is extremely rare (160)
Potential side effects : Although the exact side effects are still unknown, clinical trials have shown that it may cause the same side effects as other medications in this class like nausea, vomiting, diarrhea, constipation, and stomach discomfort
Loss of muscle mass is a key driver of bone density decline, as it reduces the dynamic strain on the skeleton, thereby accelerating disuse signaling
doi:10.3803/EnM.2019.34.3.247 Abdullah Bin Ahmed I
Thus, this case of acromegaly supports our hypothesis that GLP-1 analogs are more effective than DPP-4 inhibitors for pasireotide-induced hyperglycemia
Renal effects of dpp-4 inhibitor sitagliptin or glp-1 receptor agonist liraglutide in overweight patients with type 2 diabetes: a 12-week, randomized, double-blind, placebo-controlled trial
