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In clinicaltrials of Ozempic and Wegovy, nausea was reported in: 15.8 percent of those taking a 0.5 milligram (mg) dose of semaglutide 20.3 percent of those taking a 1 mg dose 44 percent of those taking a 2.4 mg dose These were all semaglutide injections, but nausea is also the most common side effect of Rybelsus, a semaglutide tablet

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