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Older anti-obesity medications weren't nearly as effective for weight loss as semaglutide and the other newer compounds, like tirzepatide (the active ingredient in diabetes medication Mounjaro), Horn says
Both drugs are generally avoided in pregnancy and certain rare personal or family histories of medullary thyroid cancer, and the doctor will review the history before prescribing
This decision followed a comprehensive FDA review that found no increased risk of suicidal thoughts or behaviors associated with GLP-1 use