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The SURMOUNT-4 trial showed participants regained approximately two-thirds of their lost weight within one year of stopping treatment, highlighting obesity's chronic nature and the likely need for long-term medication use combined with lifestyle modifications

We used the BACS composite score as an overall indicator for neurocognitive function

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While Wegovy is FDA-approved for weight loss, Ozempic and Mounjaro arent

FEBS Lett 581:29472953 Eydallin G, Montero M, Almagro G, Sesma MT, Viale AM, Muoz FJ, Rahimpour M, Baroja-Fernndez E, Pozueta-Romero J (2010) Genome-wide screening of genes whose enhanced expression affects glycogen accumulation in Escherichia coli