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In other words, the schedule is a sensible default that a clinician can adjust, not a fixed rule you should try to bend on your own

10.1016/j.clinthera.2019.04.018 47 GuoQ.WangY.XuD.NossentJ.PavlosN

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Proper sterile procedure is absolutely non-negotiable

It can also rise in noncancer condition such as tubo-ovarian abscess

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