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Mild symptoms may be observed briefly with oral hydration and analgesia, but persistent or recurrent pain merits imaging and urinalysis

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Preventing Weight Regain Studies show that many individuals regain weight after losing it

Aging is associated with high basal levels of circulating corticosteroids, although there is not always a correlation between plasma ACTH and corticosteroids (233-235)

These findings support the idea that receptor specificity and structural design help reduce off-target endocrine activation