Unlike tirzepatide, which activates both GLP-1 and GIP receptors, MariTide is a GIPR antagonist antibody/GLP-1R peptide agonist conjugate which means that it activates GLP-1 receptors while blocking GIP responses
(12) M Macvanin, Z Gluvic, J Radovanovic, M Essack, et al (2023) New insights on the cardiovascular effects of IGF-1 Frontiers in Endocrinology (Lausanne), 2023 Feb 9, Volume 14, Page 1142644
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