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While generally harmless, these bumps can affect how well the medication gets absorbed

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Diabetes Obes Metab (2017) 19(10):143645.10.1111/dom.13024 102 FriasJPBastyrEJIIIVignatiLTschopMHSchmittCOwenKet alThe sustained effects of a dual GIP/GLP-1 receptor agonist, NNC0090-2746, in patients with type 2 diabetes

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However, direct comparisons require caution because: Trial lengths differed Dosing protocols differed Patient populations differed Long-term orforglipron data is still developing A 5% to 10% reduction in body weight can still produce clinically meaningful improvements in blood pressure, insulin sensitivity, mobility, and metabolic health

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