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doi: 10.3389/fimmu.2026.1734880 Received 29 October 2025 Revised 06 March 2026 Accepted 09 March 2026 Published 30 March 2026 Volume 17 - 2026 Edited by Liping Feng, Duke University, United States Reviewed by Akihiro Nakamura, Kyoto Prefectural University of Medicine, Japan Simn Quetzalcoatl Rodrguez-Lara, Tecnologico de Monterrey Campus Puebla, Mexico Updates Copyright 2026 Wang, Wang, Ji, Lou, Yuan, Cui, Xiang and Zhou

Some protocols split the daily dose into morning and evening injections for more consistent tissue levels, taking advantage of the peptide's short half-life by maintaining more frequent, lower doses

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Differential guide scores in the indicated cell lines upon treatment with 20 M BSO (right)