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In septic mice, semaglutide attenuated sickness behavior, hypothermia, systemic inflammation, and lung injury through the downregulation of pro-inflammatory cytokines (TNF- , IL-1, IL-6, CXCL1), suppression of neutrophil infiltration, and decreased expression of genes associated with tissue remodeling and inflammation (Mmp9, Timp1, Ly6g)

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The rising prevalence of diabetes and obesity globally is a major public health concern and necessitates early treatment

[DOI] [PubMed] [Google Scholar] 69.Zhu J., Yan Y., Qiu X., Lin S., Wen J

"It wasn't until I took medication that changed my chemistry that I realized that the 'food chatter' in my brain wasn't my fault." In conversations with Insider, semaglutide patients reported strikingly similar experiences with the drug namely, a sudden end to cravings and an abrupt quieting of obsessive thoughts around food

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