Over a month of weekly injections, you receive 3-5mg less total tirzepatide than planned
Short-acting GLP-1RAs are administered before a meal, and have a greater effect on gastric emptying and postprandial glucose, primarily after the meal, whereas long-acting GLP-1RAs have less of an effect on gastric emptying and postprandial glucose excursions, but a more pronounced effect on fasting blood glucose and weight loss (140)
Studies in rodent models have evaluated its effects on bone repair, tendon-to-bone healing, and ligament recovery
Over time this can speed up the aging process
Current evidence suggests that GLP-1 medications, when used with appropriate patient selection and monitoring, likely do not pose significant long-term threats to vision for most patients and may contribute to better overall ocular outcomes through improved metabolic control
Biomed Pharmacother 2003;57(3-4):145-155