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Patients should also report persistent fatigue, headache, or malaise that significantly impacts daily functioning or does not improve within one to two weeks of medication initiation or dose adjustment

is exhausting and frustrating

Patients experiencing persistent low mood, thoughts of self-harm, or significant anxiety whilst taking Wegovy should seek prompt medical advice

2022;186(6):P35P52

For comparative studies with native GLP-1, include DPP-IV inhibitors in all assay buffers when native GLP-1 is included as a comparator to prevent rapid DPP-IV degradation that would confound Semaglutide versus native GLP-1 concentration-response comparisons

Staying on a regular weekly schedule keeps semaglutide's appetite-suppressing benefits more stable throughout your treatment cycle