J Biol Chem 272 : 1000410012
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However, the ghrelin receptor couples to multiple intracellular signaling pathways (Gq/11, Gs, beta-arrestin), and different agonists can preferentially activate different pathways a concept termed biased agonism or functional selectivity
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In an often-cited 1993 study, GHK-Cu increased the accumulation of connective tissue in experimental wounds in rats, supporting a real role in repair