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5 SNAC works by temporarily raising the pH around the tablet in the stomach, thereby protecting semaglutide from acid degradation

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In the off-label study, 70% of men rated themselves as at least a little better on the PGI-I after starting PT-141.Similarly, the Global Assessment Question (GAQ) used in some ED trials simply asks, Has the treatment improved your erections? a yes/no that provides a quick snapshot of perceived efficacy

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The difference may partly reflect dose equivalency issues in trials rather than a true pharmacological difference

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