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The time required to significantly change the BMI may be longer than the time to alter the microbial community (104)

In addition to the effects of necrosis and apoptosis, other regulatory pathways, such as autophagy and necroptosis, have been proposed to play important roles in fat graft survival [26, 27]

in vitro experiments showed that SGK1 knockdown alleviated erastin-induced downregulation of Slc7a11, GPX4, GSH, and GSSG, while reducing lipid peroxidation, iron accumulation, and mitochondrial damage upregulation, suggesting that SGK1 modulates ferroptosis processes through inflammatory pathways in CHD (44)

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Polley MY, Leung SC, McShane LM, Gao D, Hugh JC, Mastropasqua MG, et al