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Patients should seek urgent medical attention if they experience signs of a severe allergic reaction (such as widespread rash, facial or tongue swelling, or breathing difficulties) or extensive skin reactions

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[6] However, exploratory analyses suggested potential benefits in participants with obesity (BMI 30 kg/m)

Patients may benefit from integration with Functional Medicine to address root-cause metabolic contributors in addition to treatment of obesity, Longevity Medicine to support preventive and performance-based goals, and Hormone Replacement Therapy when endocrine factors contribute to weight resistance

Patients with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) should avoid these medications due to the potential risk of thyroid C-cell tumors

Geary, N