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Hankosky, PhD, senior director of Cardiometabolic Health, Health Economics and Outcomes Research at Eli Lilly & Company, and corresponding author of this study, confirmed for Medical News Today that the participants were taking Mounjaro as an off-label treatment for weight management at the discretion of their prescribing physician. During their study, researchers also reported that about 32% of participants who started tirzepatide had class 3 obesity with a BMI of 40 kg/m 2 or more
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Moreover, a previous study showed that overexpression of CPT1A can reverse the inflammation and fibrosis status of the kidneys by restoring mitochondrial homeostasis [19]
