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This ML-based approach has potential clinical application in the diagnosis and management of hereditary angioedema, and may have utility in scenarios where laboratory testing is not readily available or the management strategy remains uncertain (Fig

Results for individual cytokines above detection threshold can be found in the Supplement

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Beyond availability, the brand-name medication carries high out-of-pocket costs even with insurance coverage, often requiring prior authorization and copayments exceeding $200 per month