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Its distinct from traditional diabetes medications like metformin , which decreases glucose production in the liver and increases insulin sensitivity

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Use of MOUNJARO for this indication is supported by a 30-week, randomized, double-blind, placebo-controlled trial with a 22-week open label extension in 99 pediatric patients [see Clinical Studies (14.5)]

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Experimental studies investigate MOTS-C for its interaction with nuclear gene expression, AMPK-associated metabolic sign

"The dopamine system is what makes drugs rewarding, and if you interfere, the drugs are no longer rewarding," study author and NIDA director Dr