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GLP-1 receptors are found in the hypothalamus (appetite regulation), hippocampus (memory formation), brainstem (nausea responses), ventral tegmental area and nucleus accumbens (reward circuits), amygdala (emotional processing), prefrontal cortex (executive function), and substantia nigra (motor control)
From a healthcare system perspective, the availability of oral GLP-1 drugs may also influence prescribing patterns
These findings have implications for dilated cardiomyopathy research, post-infarction remodeling studies, and investigations into preventing adverse cardiac remodeling that leads to chronic heart failure
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