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Their uptake has varied across patient populations, raising questions about evolving clinical practice

Clinical data shows significant improvements in depression scores, anxiety measures, and overall quality of life assessments in people who achieve meaningful weight loss with GLP-1 therapy

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Clinical studies We split this section between studies of GLP-1RAs in people with mood disorders and studies of mood symptoms in patients with other medical conditions taking GLP-1RAs (Tables 4 and 5, and Extended Data Tables 5 and 6)