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Authors' contributions YW wrote the manuscript, conceived the topic of review and collected the data

Mechanistically, Sermorelin: Binds to GHRH receptors on somatotroph cells in the anterior pituitary, stimulating synthesis and pulsatile release of endogenous GH

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Pinch your skin: With the hand not holding the syringe, pinch a chunk of skin between your thumb and index finger, and hold it

Metabolic signalling