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Wells were washed 5 times with PBS-T and binding of the antibodies to bound NTD-H were detected colorimetrically by using the OPD substrate and reading at 492 nm using the Labsystems IEMS reader

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Pfizer plans to accelerate the clinical development of Metseras candidates, targeting a Phase 3 launch for MET-097i and advancing other pipeline drugs towards approval

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By suppressing appetite and reducing cravings, these drugs alter the brain's normal reward responses to food