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This is due to saturation of the IGF-1R receptors, resulting in the remaining IGF-1 circulating in the blood attaching to bone and gastrointestinal tissue [1, 16]

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Up to 1ml can be injected into this site in neonates, up to 3mls in children and up to 5mls in adults

doi: 10.1016/j.archger.2006.02.003

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