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A: Tirzepatide is a strong option for patients who had an inadequate response to semaglutide (less than 10% body weight loss at maximum tolerated dose), those with prominent insulin resistance, and patients who require more aggressive weight reduction to manage obesity-related comorbidities

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7E), suggesting potential unconventional secretion mechanisms

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[DOI] [PubMed] [Google Scholar] 12.Inagaki N, Seino Y, Takeda J, et al